Recombinant Human NRP1 protein, His-tagged
Cat.No. : | NRP1-806H |
Product Overview : | Recombinant Human NRP1 protein (483-644aa) was fused to His-tag and expressed in E.coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Form : | Lyophilized from sterile PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH7.4). 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
Molecular Mass : | 32 kDa |
AA Sequence : | EWLQIDLGEEKIVRGIIIQGGKHRE NKVFMRKFKIGYSNNGSDWKMIMDD SKRKAKSFEGNNNYDTPELRTFPAL STRFIRIYPERATHGGLGLRMELLG CEVEAPTAGPTTPNGNLVDECDDDQ ANCHSGTGDDFQLTGGTTVLATEKP TVIDSTIQSGIK |
Purity : | 90%, by SDS-PAGE with Coomassie Brilliant Blue staining. |
Storage : | Store for up to 12 months at -20 to -80 centigrade as lyophilized powder. Short-term storage: Store at 2-8 centigrade for (1-2 weeks). Long-term storage: Aliquot and store at -20 to -80 centigrade for up to 3 months, buffer containing 50% glycerol is recommended for reconstitution. Avoid repeat freeze-thaw cycles. |
Reconstitution : | Reconstitute at 0.25 µg/μl in 200 μl sterile water for short-term storage. Reconstitution with 200 μl 50% glycerol solution is recommended for longer term storage. If a different concentration is needed for your purposes please adjust the reconstitution |
Shipping : | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
Gene Name : | NRP1 |
Official Symbol : | NRP1 |
Synonyms : | NP1; NRP; BDCA4; CD304; VEGF165R |
Gene ID : | 8829 |
mRNA Refseq : | NM_003873.7 |
Protein Refseq : | NP_003864.5 |
MIM : | 602069 |
UniProt ID : | O14786 |
Products Types
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◆ Lysates | ||
NRP1-1763HCL | Recombinant Human NRP1 cell lysate | +Inquiry |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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- Q&As
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Q&As (6)
Ask a questionIt may be involved in the processes of angiography, inflammation, fibrosis and other processes in the lungs, and is related to the occurrence and development of lung diseases.
The high expression of NRP1 may be related to factors such as the aggressiveness of the tumor and the increased angiogenesis of the tumor.
Yes, NRP1, as a molecule with important biological functions and clinical significance, can be targeted as a target therapy.
This protein can be used as a potential marker in clinical diagnosis for tumor diagnosis and prognosis evaluation.
Yes, NRP1 may be related to the metabolism of drugs, the response to drug treatment, etc., which affects the efficacy and side effects of drugs.
NRP1 may be involved in the regulation of autoimmune responses, inflammatory responses, etc., and is related to the occurrence and development of immune diseases.
Customer Reviews (3)
Write a reviewThe protein has a moderate molecular weight and is convenient to use.
NRP1 can be easily used and measured in experiment.
NRP1 has a high purity.
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