Recombinant Human NSD3 Protein, GST-tagged

• Cat.No.: NSD3-152H
• Product Overview: Recombinant human NSD3 protein with a N-terminal GST tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 1021-1322 (N- and C-terminal truncation)
• Description: This gene is related to the Wolf-Hirschhorn syndrome candidate-1 gene and encodes a protein with PWWP (proline-tryptophan-tryptophan-proline) domains. This protein methylates histone H3 at lysine residues 4 and 27, which represses gene transcription. Two alternatively spliced variants have been described.
• Molecular Mass: 61.2 kDa
• Purity: ≥90% estimated by SDS-PAGE
• Stability: ≥ 6 months
• Storage: At -80 centigrade.
• Storage Buffer: 50 mM Tris, pH 8.0, containing 150 mM sodium chloride and 20% glycerol

Gene Information

• Gene Name: NSD3 nuclear receptor binding SET domain protein 3 [ Homo sapiens (human) ]
• Official Symbol: NSD3
• Synonyms: NSD3; nuclear receptor binding SET domain protein 3; KMT3F; KMT3G; WHISTLE; WHSC1L1; pp14328; histone-lysine N-methyltransferase NSD3; Wolf-Hirschhorn syndrome candidate 1-like 1; nuclear SET domain-containing protein 3; protein whistle; EC 2.1.1.370; EC 2.1.1.371
• Gene ID: 54904
• mRNA Refseq: NM_017778
• Protein Refseq: NP_060248
• MIM: 607083
• UniProt ID: Q9BZ95