Recombinant Human NSMAF protein, MYC/DDK-tagged NSMAF-524H

Recombinant Human NSMAF protein, MYC/DDK-tagged


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Recombinant Human NSMAF protein, MYC/DDK-tagged

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Cat.No. : NSMAF-524H
Product Overview : Recombinant Human NSMAF, transcript variant 1, fused with MYC/DDK tag at C-terminal was expressed in HEK293.
Description : This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.
Source : HEK293
Species : Human
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 104.2 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : NSMAF neutral sphingomyelinase (N-SMase) activation associated factor [ Homo sapiens ]
Official Symbol : NSMAF
Synonyms : NSMAF; neutral sphingomyelinase (N-SMase) activation associated factor; protein FAN; FAN; factor associated with N-SMase activation; factor associated with neutral sphingomyelinase activation;
Gene ID : 8439
mRNA Refseq : NM_003580
Protein Refseq : NP_003571
MIM : 603043
UniProt ID : Q92636
Chromosome Location : 8q12-q13
Pathway : TNF receptor signaling pathway, organism-specific biosystem; TNF-alpha/NF-kB Signaling Pathway, organism-specific biosystem;
Function : protein binding; receptor signaling protein activity;

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