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Recombinant Human NSMAF protein, MYC/DDK-tagged

Cat.No. : NSMAF-524H
Product Overview : Recombinant Human NSMAF, transcript variant 1, fused with MYC/DDK tag at C-terminal was expressed in HEK293.
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  • Gene Information
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Description : This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 104.2 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : NSMAF neutral sphingomyelinase (N-SMase) activation associated factor [ Homo sapiens ]
Official Symbol : NSMAF
Synonyms : NSMAF; neutral sphingomyelinase (N-SMase) activation associated factor; protein FAN; FAN; factor associated with N-SMase activation; factor associated with neutral sphingomyelinase activation;
Gene ID : 8439
mRNA Refseq : NM_003580
Protein Refseq : NP_003571
MIM : 603043
UniProt ID : Q92636
Chromosome Location : 8q12-q13
Pathway : TNF receptor signaling pathway, organism-specific biosystem; TNF-alpha/NF-kB Signaling Pathway, organism-specific biosystem;
Function : protein binding; receptor signaling protein activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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