"NSMAF" Related Products


Recombinant Human NSMAF protein, MYC/DDK-tagged

Cat.No.: NSMAF-524H
Product Overview: Recombinant Human NSMAF, transcript variant 1, fused with MYC/DDK tag at C-terminal was expressed in HEK293.
Description: This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.
Source: HEK293
Species: Human
Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass: 104.2 kDa
Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration: >50 ug/mL as determined by microplate BCA method
Gene Name: NSMAF neutral sphingomyelinase (N-SMase) activation associated factor [ Homo sapiens ]
Official Symbol: NSMAF
Synonyms: NSMAF; neutral sphingomyelinase (N-SMase) activation associated factor; protein FAN; FAN; factor associated with N-SMase activation; factor associated with neutral sphingomyelinase activation;
Gene ID: 8439
mRNA Refseq: NM_003580
Protein Refseq: NP_003571
MIM: 603043
UniProt ID: Q92636
Chromosome Location: 8q12-q13
Pathway: TNF receptor signaling pathway, organism-specific biosystem; TNF-alpha/NF-kB Signaling Pathway, organism-specific biosystem;
Function: protein binding; receptor signaling protein activity;

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