"NTRK1" Related Products

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Recombinant Human NTRK1 Protein, DDK/His-tagged

Cat.No.: NTRK1-296H
Product Overview: Recombinant Human NTRK1(Ala33-Gly417), transcript variant 1, fused with DDK/His tag at C-terminal was expressed in HEK293.
Description: This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
Source: HEK293
Species: Human
Tag : DDK/His
Form: 1 x PBS, pH7.4, 10% glycerol
Molecular Mass: 45 kDa
Protein length: Ala33-Gly417
Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration: >50 ug/mL as determined by microplate BCA method
Gene Name: NTRK1 neurotrophic tyrosine kinase, receptor, type 1 [ Homo sapiens ]
Official Symbol: NTRK1
Synonyms: NTRK1; neurotrophic tyrosine kinase, receptor, type 1; high affinity nerve growth factor receptor; MTC; TRK; TRKA; gp140trk; Oncogene TRK; tyrosine kinase receptor A; tropomyosin-related kinase A; TRK1-transforming tyrosine kinase protein; TRK1; Trk-A; p140-TrkA; DKFZp781I14186;
Gene ID: 4914
mRNA Refseq: NM_001012331
Protein Refseq: NP_001012331
MIM: 191315
UniProt ID: P04629

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