Recombinant Human NTRK1 Protein, Fc/His-tagged
| Cat.No. : | NTRK1-2030H |
| Product Overview : | Recombinant Human TrkA Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Ala33-Glu407) of human TrkA (Accession #NP_001012331.1) fused with an Fc, 6×His tag at the C-terminus. |
- Specification
- Gene Information
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| Description : | This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | Fc/His |
| Form : | Lyophilized from sterile PBS, pH 7.4, 5 % trehalose, 5 % mannitol. |
| Protein length : | Ala33-Glu407 |
| Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Purity : | > 90% as determined by SDS-PAGE |
| Stability : | Samples are stable for up to twelve months from date of receipt at -70ºC. |
| Storage : | Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
| Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents. |
| Gene Name : | NTRK1 neurotrophic tyrosine kinase, receptor, type 1 [ Homo sapiens ] |
| Official Symbol : | NTRK1 |
| Synonyms : | NTRK1; neurotrophic tyrosine kinase, receptor, type 1; high affinity nerve growth factor receptor; MTC; TRK; TRKA; gp140trk; Oncogene TRK; tyrosine kinase receptor A; tropomyosin-related kinase A; TRK1-transforming tyrosine kinase protein; TRK1; Trk-A; p140-TrkA; DKFZp781I14186; |
| Gene ID : | 4914 |
| mRNA Refseq : | NM_001007792 |
| Protein Refseq : | NP_001007793 |
| MIM : | 191315 |
| UniProt ID : | P04629 |
Products Types
| ◆ Recombinant Protein | ||
| Ntrk1-4522M | Recombinant Mouse Ntrk1 Protein, Myc/DDK-tagged | +Inquiry |
| Ntrk1-16R | Recombinant Rat Ntrk1 Protein, His (Fc)-Avi-tagged | +Inquiry |
| NTRK1-130H | Recombinant Human NTRK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
| NTRK1-163N | Active Recombinant Human NTRK1 Protein | +Inquiry |
| NTRK1-01H | Active Recombinant Human NTRK1 Protein (34-407), Animal free | +Inquiry |
| ◆ Lysates | ||
| NTRK1-2147HCL | Recombinant Human NTRK1 cell lysate | +Inquiry |
| NTRK1-963CCL | Recombinant Canine NTRK1 cell lysate | +Inquiry |
| NTRK1-1086MCL | Recombinant Mouse NTRK1 cell lysate | +Inquiry |
| ◆ Assay kits | ||
| Kit-1627 | TrkA Functional Assay Kit | +Inquiry |
| Kit-1546 | U2OS TrkA Bioassay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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