"NTRK3" Related Products

Expand
Expand

Recombinant Human NTRK3 Protein, His-tagged

Cat.No.: NTRK3-161H
Product Overview: Human TrkC / NTRK3 Protein (Human TrkC, His Tag) Cys 32 - Thr 429 (Accession # AAH13693.1) was produced in human 293 cells (HEK293).
Source: HEK293
Species: Human
Tag: His
Predicted N Terminal: Cys 32
Form: Lyophilized from sterile PBS, pH7.4, 10% Trehalose.
Bio-activity: Measured by its ability to inhibit NT-3-induced proliferation of BaF-TrkB-BD mouse pro-B cells transfected with TrkB. The ED50 for this effect is typically 0.01 - 0.1 ug/mL in the presence of 40 ng/mL of recombinant human NT-3.
Molecular Mass: Human TrkC, His Tag is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 45.6 kDa. The reducing protein migrates as 80-90 kDa in SDS-PAGE due to glycosylation.
Endotoxin: Less than 1.0 EU per μg by the LAL method.
Purity: >95% as determined by SDS-PAGE.
Stability: Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage: Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Gene Name: NTRK3 neurotrophic tyrosine kinase, receptor, type 3 [ Homo sapiens ]
Official Symbol: NTRK3
Synonyms: NTRK3; neurotrophic tyrosine kinase, receptor, type 3; NT-3 growth factor receptor; TRKC; GP145-TrkC; ETV6-NTRK3 fusion; tyrosine kinase receptor C; ETS related protein-neurotrophic receptor tyrosine kinase fusion protein; gp145(trkC);
Gene ID: 4916
mRNA Refseq: NM_001007156
Protein Refseq: NP_001007157
MIM: 191316
UniProt ID: Q16288
Chromosome Location: 15q24-q25
Pathway: Neurotrophic factor-mediated Trk receptor signaling, organism-specific biosystem; Neurotrophin signaling pathway, organism-specific biosystem; Neurotrophin signaling pathway, conserved biosystem;
Function: ATP binding; neurotrophin binding; nucleotide binding; receptor activity; transmembrane receptor protein tyrosine kinase activity;

Online Inquiry

Note: There will be extra charge for optional service!
Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information


Price does not include shipping and packaging costs.Request quote for final price.

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.