Recombinant Human ORC4 Protein, MYC/DDK-tagged

• Cat.No.: ORC4-288H
• Product Overview: Recombinant human ORC4 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Description: The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. This gene encodes a subunit of the ORC complex. Several alternatively spliced transcript variants, some of which encode the same protein, have been reported for this gene. [provided by RefSeq, Oct 2010]
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 50.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: origin recognition complex subunit 4 [ Homo sapiens ]
• Official Symbol: ORC4
• Synonyms: ORC4L; ORC4P
• Gene ID: 5000
• mRNA Refseq: NM_001190881.2
• Protein Refseq: NP_001177810.1
• MIM: 603056
• UniProt ID: O43929