Recombinant Human OTUD5 Protein, MYC/DDK-tagged

• Cat.No.: OTUD5-373H
• Product Overview: Recombinant human OTUD5 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Oct 2008].
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 60.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: OTU deubiquitinase 5 [ Homo sapiens ]
• Official Symbol: OTUD5
• Synonyms: DUBA; DUBA
• Gene ID: 55593
• mRNA Refseq: NM_017602.3
• Protein Refseq: NP_060072.1
• MIM: 300713
• UniProt ID: Q96G74