Recombinant Human P2RX6 Protein, His-tagged

• Cat.No.: P2RX6-2539H
• Product Overview: Recombinant Human P2RX6 Protein (Lys61-Gly333) with a N-His tag was expressed in E. coli.

Specification

• Description: The protein encoded by this gene belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. This gene is predominantly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 22, has been identified.
• Source: E. coli
• Species: Human
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 34.4 kDa
  Accurate Molecular Mass: 34 kDa
• Protein length: Lys61-Gly333
• Endotoxin: <1.0 EU per 1µg (determined by the LAL method).
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: P2RX6 purinergic receptor P2X, ligand-gated ion channel, 6 [ Homo sapiens (human) ]
• Official Symbol: P2RX6
• Synonyms: P2RX6; purinergic receptor P2X, ligand-gated ion channel, 6; P2RXL1, purinergic receptor P2X like 1, orphan receptor; P2X purinoceptor 6; MGC129625; P2X6; P2XM; ATP receptor; purinoceptor P2X6; purinoreceptor P2X6; skeletal muscle-expressed P2X; purinergic receptor P2X-like 1, orphan receptor; P2RXL1
• Gene ID: 9127
• mRNA Refseq: NM_001159554
• Protein Refseq: NP_001153026
• MIM: 608077
• UniProt ID: O15547