Recombinant Human P4HB Protein (18-508 aa), His-tagged
| Cat.No. : | P4HB-1478H |
| Product Overview : | Recombinant Human P4HB Protein (18-508 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Cancer. Protein Description: Full Length of Mature Protein. |
- Specification
- Gene Information
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| Description : | This multifunctional protein catalyzes the formation, breakage and rearrangent of disulfide bonds. At the cell surface, ses to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. May therefore cause structural modifications of exofacial proteins. Inside the cell, ses to form/rearrange disulfide bonds of nascent proteins. At high concentrations, functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, facilitates aggregation (anti-chaperone activity). May be involved with other chaperones in the structural modification of the TG precursor in hormone biogenesis. Also acts a structural subunit of various enzymes such as prolyl 4-hydroxylase and microsomal triacylglycerol transfer protein MTTP. |
| Source : | Yeast |
| Species : | Human |
| Tag : | His |
| Form : | Tris-based buffer,50% glycerol |
| Molecular Mass : | 57.3 kDa |
| Protein length : | 18-508 aa |
| AA Sequence : | DAPEEEDHVLVLRKSNFAEALAAHK YLLVEFYAPWCGHCKALAPEYAKAA GKLKAEGSEIRLAKVDATEESDLAQ QYGVRGYPTIKFFRNGDTASPKEYT AGREADDIVNWLKKRTGPAATTLPD GAAAESLVESSEVAVIGFFKDVESD SAKQFLQAAEAIDDIPFGITSNSDV FSKYQLDKDGVVLFKKFDEGRNNFE GEVTKENLLDFIKHNQLPLVIEFTE QTAPKIFGGEIKTHILLFLPKSVSD YDGKLSNFKTAAESFKGKILFIFID SDHTDNQRILEFFGLKKEECPAVRL ITLEEEMTKYKPESEELTAERITEF CHRFLEGKIKPHLMSQELPEDWDKQ PVKVLVGKNFEDVAFDEKKNVFVEF YAPWCGHCKQLAPIWDKLGETYKDH ENIVIAKMDSTANEVEAVKVHSFPT LKFFPASADRTVIDYNGERTLDGFK KFLESGGQDGAGDDDDLEDLEEAEE PDMEEDDDQKAVKDEL |
| Purity : | > 90% as determined by SDS-PAGE. |
| Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
| Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
| Concentration : | A hardcopy of COA with reconstitution instruction is sent along with the products. |
| Gene Name : | P4HB prolyl 4-hydroxylase, beta polypeptide [ Homo sapiens ] |
| Official Symbol : | P4HB |
| Synonyms : | P4HB; DSI; GIT; P4Hbeta; PDI; PDIA1; PO4HB; PROHB; p55; PHDB; PO4DB; ERBA2L; |
| Gene ID : | 5034 |
| mRNA Refseq : | NM_000918 |
| Protein Refseq : | NP_000909 |
| MIM : | 176790 |
| UniProt ID : | P07237 |
Products Types
| ◆ Recombinant Protein | ||
| P4hb-4642M | Recombinant Mouse P4hb Protein, Myc/DDK-tagged | +Inquiry |
| P4HB-2042C | Recombinant Cricetulus Griseus P4HB Protein (20-509 aa), His-tagged | +Inquiry |
| P4HB-3904R | Recombinant Rat P4HB Protein, His (Fc)-Avi-tagged | +Inquiry |
| P4hb-1450M | Recombinant Mouse P4hb protein, His & GST-tagged | +Inquiry |
| P4HB-33M | Recombinant Mouse P4HB Protein, His-tagged | +Inquiry |
| ◆ Lysates | ||
| P4HB-2764HCL | Recombinant Human P4HB cell lysate | +Inquiry |
| P4HB-2121MCL | Recombinant Mouse P4HB cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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