Recombinant Human PA28G Protein, His-tagged
Cat.No. : | PA28G-307H |
Product Overview : | Recombinant Human PA28G Protein is produced by Bacteria expression system. This protein is fused with a His tag. |
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Species : | Human |
Source : | E.coli |
Tag : | His |
Description : | PA28 (also called the 11S regulatory complex) is another activator of the 20S proteasome, which assembles on either one or both ends of the 20S proteasome in an ATP-independent manner. PA28 can greatly enhance the peptidase activities of the 20S proteasome, but not for degradation of ubiquitinated proteins. The PA28 activator is a complex of two alternating homologous subunits, PA28α and PA28β, which assembles as a hexameric ring with an α3β3 stoichiometry. PA28α and PA28β are induced by interferon. Functionally, PA28 enhances the generation of class I peptides for antigen presentation. The third subunit, PA28γ, was recently identified in the nucleus. Recombinant PA28α and PA28β form a heptomeric ring; whereas PA28γ forms a hexameric ring. All of them can stimulate the peptidase activities of the 20S proteasome. |
Form : | 20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol |
Molecular Mass : | 29.5 kDa |
Purity : | > 95 % by SDS-PAGE |
Storage : | Store at -80 centigrade; avoid multiple freeze-thaw cycles. |
Gene Name | PSME3 proteasome activator subunit 3 ( Homo sapiens (human) ) |
Official Symbol | PSME3 |
Synonyms | PSME3; Ki; REG-GAMMA; PA28-gamma; PA28gamma; PA28 gamma |
Gene ID | 10197 |
mRNA Refseq | NM_176863 |
Protein Refseq | NP_789839 |
UniProt ID | P61289 |
◆ Recombinant Proteins | ||
PA28G-307H | Recombinant Human PA28G Protein, His-tagged | +Inquiry |
Not For Human Consumption!
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