Recombinant Human PA28G Protein, His-tagged


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Recombinant Human PA28G Protein, His-tagged

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Cat.No. : PA28G-307H
Product Overview : Recombinant Human PA28G Protein is produced by Bacteria expression system. This protein is fused with a His tag.
Description : PA28 (also called the 11S regulatory complex) is another activator of the 20S proteasome, which assembles on either one or both ends of the 20S proteasome in an ATP-independent manner. PA28 can greatly enhance the peptidase activities of the 20S proteasome, but not for degradation of ubiquitinated proteins. The PA28 activator is a complex of two alternating homologous subunits, PA28α and PA28β, which assembles as a hexameric ring with an α3β3 stoichiometry. PA28α and PA28β are induced by interferon. Functionally, PA28 enhances the generation of class I peptides for antigen presentation. The third subunit, PA28γ, was recently identified in the nucleus. Recombinant PA28α and PA28β form a heptomeric ring; whereas PA28γ forms a hexameric ring. All of them can stimulate the peptidase activities of the 20S proteasome.
Source : Bacteria
Species : Human
Tag : His
Form : 20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol
Molecular Mass : 29.5 kDa
Purity : > 95 % by SDS-PAGE
Storage : Store at -80 centigrade; avoid multiple freeze-thaw cycles.
Gene Name : PSME3 proteasome activator subunit 3 ( Homo sapiens (human) )
Official Symbol : PSME3
Synonyms : PSME3; Ki; REG-GAMMA; PA28-gamma; PA28gamma; PA28 gamma
Gene ID : 10197
mRNA Refseq : NM_176863
Protein Refseq : NP_789839
UniProt ID : P61289

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