Recombinant Human PAH Protein, MYC/DDK-tagged, C13 and N15-labeled

• Cat.No.: PAH-199H
• Product Overview: PAH MS Standard C13 and N15-labeled recombinant protein (NP_000268) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the biopterin-dependent aromatic amino acid hydroxylase protein family. The encoded phenylalanine hydroxylase enzyme hydroxylates phenylalanine to tyrosine and is the rate-limiting step in phenylalanine catabolism. Deficiency of this enzyme activity results in the autosomal recessive disorder phenylketonuria. [provided by RefSeq, Aug 2017]
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 51.8 kDa
• AA Sequence: MSTAVLENPGLGRKLSDFGQETSYI EDNCNQNGAISLIFSLKEEVGALAK VLRLFEENDVNLTHIESRPSRLKKD EYEFFTHLDKRSLPALTNIIKILRH DIGATVHELSRDKKKDTVPWFPRTI QELDRFANQILSYGAELDADHPGFK DPVYRARRKQFADIAYNYRHGQPIP RVEYMEEGKKTWGTVFKTLKSLYKT HACYEYNHIFPLLEKYCGFHEDNIP QLEDVSQFLQTCTGFRLRPVAGLLS SRDFLGGLAFRVFHCTQYIRHGSKP MYTPEPDICHELLGHVPLFSDRSFA QFSQEIGLASLGAPDEYIEKLATIY WFTVEFGLCKQGDSIKAYGAGLLSS FGELQYCLSEKPKLLPLELEKTAIQ NYTVTEFQPLYYVAESFNDAKEKVR NFAATIPRPFSVRYDPYTQRIEVLD NTQQLKILADSINSEIGILCSALQK IKTRTRPLEQKLISEEDLAANDILD YKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: PAH phenylalanine hydroxylase [ Homo sapiens (human) ]
• Official Symbol: PAH
• Synonyms: PAH; phenylalanine hydroxylase; phenylalanine-4-hydroxylase; PH; phenylalanine 4 monooxygenase; phe-4-monooxygenase; phenylalanine 4-monooxygenase; PKU; PKU1
• Gene ID: 5053
• mRNA Refseq: NM_000277
• Protein Refseq: NP_000268
• MIM: 612349
• UniProt ID: P00439