Recombinant Human PAOX Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human PAOX Protein, Myc/DDK-tagged, C13 and N15-labeled

PAOX Related Products

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Cat.No. : PAOX-5026H
Product Overview : PAOX MS Standard C13 and N15-labeled recombinant protein (NP_997010) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 34.5 kDa
AA Sequence : MESTGSVGEA PGGPRVLVVG GGIAGLGAAQ RLCGHSAFPH LRVLEATARA GGRIRSERCF GGVVEVGAHW IHGPSRGNPV FQLAAEYGLL GEKELSQENQ LVETGGHVGL PSVSYASSGA SVSLQLVAEM ATLFYGLIDQ TREFLHAAET PVPSVGEYLK KEIGQHVAGW TEDEETRKLK LAVLNSFFNL ECCVSGTHSM DLVALAPFGE YTVLPGLDCT FSKGYQGLTN CMMAALPEDT VVFEKPVKTI HWNGSFQEAA FPGETFPVSV ECEDGDRFPA HHVIVTVPLG LSTFSVGSLP DLSLSSWRLC RMKKYFCVSP KCSGETRTRP LEQKLISEED LAANDILDYK DDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : PAOX polyamine oxidase [ Homo sapiens (human) ]
Official Symbol : PAOX
Synonyms : PAOX; polyamine oxidase (exo-N4-amino); peroxisomal N(1)-acetyl-spermine/spermidine oxidase; PAO; peroxisomal N1-acetyl-spermine/spermidine oxidase; MGC45464; DKFZp434J245;
Gene ID : 196743
mRNA Refseq : NM_207127
Protein Refseq : NP_997010
MIM : 615853
UniProt ID : Q6QHF9

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