Recombinant Human PARP16 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: PARP16-4653H
• Product Overview: PARP16 MS Standard C13 and N15-labeled recombinant protein (NP_060321) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Intracellular mono-ADP-ribosyltransferase that may play a role in different processes through the mono-ADP-ribosylation of proteins involved in those processes. May play a role in the unfolded protein response (UPR), by ADP-ribosylating and activating EIF2AK3 and ERN1, two important UPR effectors. May also mediate mono-ADP-ribosylation of karyopherin KPNB1 a nuclear import factor. May not modify proteins on arginine, cysteine or glutamate residues compared to other mono-ADP-ribosyltransferases.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 36.5 kDa
• AA Sequence: MQPSGWAAAREAAGRDMLAADLRCS LFASALQSYKRDSVLRPFPASYARG DCKDFEALLADASKLPNLKELLQSS GDNHKRAWDLVSWILSSKVLTIHSA GKAEFEKIQKLTGAPHTPVPAPDFL FEIEYFDPANAKFYETKGERDLIYA FHGSRLENFHSIIHNGLHCHLNKTS LFGEGTYLTSDLSLALIYSPHGHGW QHSLLGPILSCVAVCEVIDHPDVKC QTKKKDSKEIDRRRARIKHSEGGDI PPKYFVVTNNQLLRVKYLLVYSQKP PKSRASSQLSWFSSHWFTVMISLYL LLLLIVSVINSSAFQHFWNRAKRTR TRPLEQKLISEEDLAANDILDYKDD DDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: PARP16 poly(ADP-ribose) polymerase family member 16 [ Homo sapiens (human) ]
• Official Symbol: PARP16
• Synonyms: PARP16; poly (ADP-ribose) polymerase family, member 16; C15orf30, chromosome 15 open reading frame 30; poly [ADP-ribose] polymerase 16; FLJ20509; FLJ25281; pART15; PARP-16; C15orf30
• Gene ID: 54956
• mRNA Refseq: NM_017851
• Protein Refseq: NP_060321
• UniProt ID: Q8N5Y8