Recombinant Human PARS2 Protein, His-tagged

• Cat.No.: PARS2-2550H
• Product Overview: Recombinant Human PARS2 Protein (Lys243-Val475) with a N-His tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Lys243-Val475
• Description: This gene encodes a putative member of the class II family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of proline to tRNA molecules. Mutations have been found in this gene in some patients with Alpers syndrome.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 29 kDa
  Accurate Molecular Mass: 29 kDa
• Endotoxin: <1.0 EU per 1µg (determined by the LAL method).
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: PARS2 prolyl-tRNA synthetase 2, mitochondrial (putative) [ Homo sapiens (human) ]
• Official Symbol: PARS2
• Synonyms: PARS2; prolyl-tRNA synthetase 2, mitochondrial (putative); probable proline--tRNA ligase, mitochondrial; DKFZp727A071; proline tRNA ligase 2; mitochondrial (putative); proRS; proline--tRNA ligase; proline tRNA ligase 2, mitochondrial (putative); MT-PRORS; MGC14416; MGC19467
• Gene ID: 25973
• mRNA Refseq: NM_152268
• Protein Refseq: NP_689481
• MIM: 612036
• UniProt ID: Q7L3T8