| Description : |
This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. This family member contains 6 extracellular cadherin domains, a transmembrane domain and a cytoplasmic tail differing from those of the classical cadherins. The encoded protein is a cadherin-related neuronal receptor thought to function in the establishment of specific cell-cell connections in the brain. This gene plays a role in inhibiting cancer cell motility and cell migration. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
94.9 kDa |
| AA Sequence : |
MIVLLLFALLWMVEGVFSQLHYTVQ EEQEHGTFVGNIAEDLGLDITKLSA RGFQTVPNSRTPYLDLNLETGVLYV NEKIDREQICKQSPSCVLHLEVFLE NPLELFQVEIEVLDINDNPPSFPEP DLTVEISESATPGTRFPLESAFDPD VGTNSLRDYEITPNSYFSLDVQTQG DGNRFAELVLEKPLDREQQAVHRYV LTAVDGGGGGGVGEGGGGGGGAGLP PQQQRTGTALLTIRVLDSNDNVPAF DQPVYTVSLPENSPPGTLVIQLNAT DPDEGQNGEVVYSFSSHISPRAREL FGLSPRTGRLEVSGELDYEESPVYQ VYVQAKDLGPNAVPAHCKVLVRVLD ANDNAPEISFSTVKEAVSEGAAPGT VVALFSVTDRDSEENGQVQCELLGD VPFRLKSSFKNYYTIVTEAPLDREA GDSYTLTVVARDRGEPALSTSKSIQ VQVSDVNDNAPRFSQPVYDVYVTEN NVPGAYIYAVSATDRDEGANAQLAY SILECQIQGMSVFTYVSINSENGYL YALRSFDYEQLKDFSFQVEARDAGS PQALAGNATVNILIVDQNDNAPAIV APLPGRNGTPAREVLPRSAEPGYLL TRVAAVDADDGENARLTYSIVRGNE MNLFRMDWRTGELRTARRVPAKRDP QRPYELVIEVRDHGQPPLSSTATLV VQLVDGAVEPQGGGGSGGGGSGEHQ RPSRSGGGETSLDLTLILIIALGSV SFIFLLAMIVLAVRCQKEKKLNIYT CLASDCCLCCCCCGGGGSTCCGRQA RARKKKLSKSDIMLVQSSNVPSNPA QVPIEESGGFGSHHHNQNYCYQVCL TPESAKTDLMFLKPCSPSRSTDTEH NPCGAIVTGYTDQQPDIISNGSILS NEVRLKRKDHHLSSPPSESLLTRTR PLEQKLISEEDLAANDILDYKDDDD KV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
