Recombinant Human PCDH10, His-tagged

• Cat.No.: PCDH10-7743H
• Product Overview: Recombinant Human Protocadherin10/PCDH10 is produced with our mammalian cells expression system in HEK293. The target protein is expressed with sequence (Gin19Thr715) of Human PCDH10 fused with a polyhistidine tag at the Cterminus.

Specification

• Description: Protocadherin10 (PCDH10) is a singlepass type I membrane protein that contains six extracellular cadherin domains, one transmembrane domain and one cytoplasmic tail differing from those of the classical cadherins. As a potential calciumdependent celladhesion neuronal receptor, it may plays a role in the establishment and function of specific cellcell connections in the brain. PCDH10 moderately expressed in all regions of the brain examined, as well as in testis and ovary, and low expression in all other tested tissues.
• Source: HEK293 Cells
• Species: Human
• Tag: His
• Form: Lyophilized from a 0.2 μM filtered solution of 20mM PB, 150mM NaCl, pH 7.4
• AA Sequence: QLHYTVQEEQ EHGTFVGNIA EDLGLDITKL SARGFQTVPN SRTPYLDLNL ETGVLYVNEK IDREQICKQ SPSCVLHLEV FLENPLELFQ VEIEVLDIND NPPSFPEPDL TVEISESATP G TRFPLESA FDPDVGTNSL RDYEITPNSY FSLDVQTQGD GNRFAELVLE KPLDREQQAV HR YVLTAVD GGGGGGVGEG GGGGGGAGLP PQQQRTGTAL LTIRVLDSND NVPAFDQPVY TVS LPENSP PGTLVIQLNA
• Purity: Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
• Notes: For research use only.
• Storage: Lyophilized protein should be stored at less than 20°C. though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C. for 2-7 days.Aliquots of reconstituted samples are stable at less than 20°C. for 3 months.

Gene Information

• Gene Name: PCDH10 protocadherin 10 [ Homo sapiens ]
• Official Symbol: PCDH10
• Synonyms: PCDH10; protocadherin 10; protocadherin-10; KIAA1400; OL PCDH; ortholog of OL-pcdh; PCDH19; OL-PCDH; MGC133344; DKFZp761O2023
• Gene ID: 57575
• mRNA Refseq: NM_032961
• Protein Refseq: NP_116586
• MIM: 608286
• UniProt ID: Q9P2E7
• Chromosome Location: 4q28.3
• Function: calcium ion binding