Recombinant Human PCSK1N Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: PCSK1N-5677H
• Product Overview: PCSK1N MS Standard C13 and N15-labeled recombinant protein (NP_037403) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene functions as an inhibitor of prohormone convertase 1, which regulates the proteolytic cleavage of neuroendocrine peptide precursors. The proprotein is further processed into multiple short peptides. A polymorphism within this gene may be associated with obesity.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 27.37 kDa
• AA Sequence: MAGSPLLWGPRAGGVGLLVLLLLGL FRPPPALCARPVKEPRGLSAASPPL AETGAPRRFRRSVPRGEAAGAVQEL ARALAHLLEAERQERARAEAQEAED QQARVLAQLLRVWGAPRNSDPALGL DDDPDAPAAQLARALLRARLDPAAL AAQLVPAPVPAAALRPRPPVYDDGP AGPDAEEAGDETPDVDPELLRYLLG RILAGSADSEGVAAPRRLRRAADHD VGSELPPEGVLGALLRVKRLETPAP QVPARRLLPPTRTRPLEQKLISEED LAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor [ Homo sapiens (human) ]
• Official Symbol: PCSK1N
• Synonyms: PCSK1N; proprotein convertase subtilisin/kexin type 1 inhibitor; proSAAS; SAAS; pro-SAAS; proprotein convertase 1 inhibitor; granin-like neuroendocrine peptide; PROSAAS
• Gene ID: 27344
• mRNA Refseq: NM_013271
• Protein Refseq: NP_037403
• MIM: 300399
• UniProt ID: Q9UHG2