Recombinant Human PDCD10 Protein, His-tagged

• Cat.No.: PDCD10-151H
• Product Overview: Recombinant Human programmed cell death 10(PDCD10) protein, transcript variant 1(NM_007217), with a His tag, was expressed in human cells.

Specification

• Description: This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified.
• Source: Human Cells
• Species: Human
• Tag: His
• Form: Purified protein formulated in a sterile solution of TBS buffer, pH7.291, without any preservatives.
• Molecular Mass: 24.9kD
• Endotoxin: Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
• Purity: >90% by SDS-PAGE gel and Coomassie Blue staining
• Applications: Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies.

Gene Information

• Gene Name: PDCD10 programmed cell death 10 [ Homo sapiens ]
• Official Symbol: PDCD10
• Synonyms: PDCD10; programmed cell death 10; CCM3, cerebral cavernous malformations 3; programmed cell death protein 10; TFAR15; apoptosis-related protein 15; TF-1 cell apoptosis-related protein 15; cerebral cavernous malformations 3 protein; CCM3; MGC1212; MGC24477
• Gene ID: 11235
• mRNA Refseq: NM_007217
• Protein Refseq: NP_009148
• MIM: 609118
• UniProt ID: Q9BUL8