"PDCD10" Related Products

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Recombinant Human PDCD10S1 protein

Cat.No.: PDCD10-10H
Product Overview: Recombinant Human PDCD10(Met1-Ala212) was expressed in E. coli.
Description: Function of this protein: Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity and STK26 activity. Important for cell migration, and for normal structure and assembly of the Golgi complex. Important for KDR/VEGFR2 signaling. Increases the stability of KDR/VEGFR2 and prevents its breakdown. Required for normal cardiovascular development. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development (By similarity).
Source: E. coli
Species: Human
Form: Protein in [25mM TrisHCl, pH7.3.] was 0.22 um filtered before lyophilized. Usually protectant (mannitol or trehalose) was added before lyophilization.
Molecular Mass: 24.9KD
Endotoxin: Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Purity: Greater than 95% as determined by reducing SDS-PAGE.
Storage: Lyophilized form is stable at room temperature for 3 weeks. Keep at -20 centigrade for long term storage. After reconstitution, store at 4 centigrade for 2-7 days or at below -20 centigrade for up to 3 months.
Reconstitution: Reconstitute lyophilized powder with water to no less than 100 ug/ml, solubilize at RT for 30 min with occasional gentle mixing. It is recommended that 0.1% HSA (SDP1139) be added as a carrier protein for long term storage.
Gene Name: PDCD10 programmed cell death 10 [ Homo sapiens ]
Official Symbol: PDCD10
Synonyms: PDCD10; programmed cell death 10; CCM3, cerebral cavernous malformations 3; programmed cell death protein 10; TFAR15; apoptosis-related protein 15; TF-1 cell apoptosis-related protein 15; cerebral cavernous malformations 3 protein; CCM3; MGC1212; MGC24477;
Gene ID: 11235
mRNA Refseq: NM_007217
Protein Refseq: NP_009148
MIM: 609118
UniProt ID: Q9BUL8
Chromosome Location: 3q26.1
Pathway: Validated targets of C-MYC transcriptional activation, organism-specific biosystem;
Function: protein N-terminus binding; protein binding; protein homodimerization activity;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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