- Human(7)
- Mouse(1)
- Rhesus Macaque(1)
Recombinant Human PDE1A Protein, Myc/DDK-tagged, C13 and N15-labeled
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Cat.No. : | PDE1A-1787H Optional Service: Optional requirements on this protein |
Product Overview : | PDE1A MS Standard C13 and N15-labeled recombinant protein (NP_005010) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
Description : | Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+). |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 62.3 kDa |
AA Sequence : | MGSSATEIEE LENTTFKYLT GEQTEKMWQR LKGILRCLVK QLERGDVNVV DLKKNIEYAA SVLEAVYIDE TRRLLDTEDE LSDIQTDSVP SEVRDWLAST FTRKMGMTKK KPEEKPKFRS IVHAVQAGIF VERMYRKTYH MVGLAYPAAV IVTLKDVDKW SFDVFALNEA SGEHSLKFMI YELFTRYDLI NRFKIPVSCL ITFAEALEVG YSKYKNPYHN LIHAADVTQT VHYIMLHTGI MHWLTELEIL AMVFAAAIHD YEHTGTTNNF HIQTRSDVAI LYNDRSVLEN HHVSAAYRLM QEEEMNILIN LSKDDWRDLR NLVIEMVLST DMSGHFQQIK NIRNSLQQPE GIDRAKTMSL ILHAADISHP AKSWKLHYRW TMALMEEFFL QGDKEAELGL PFSPLCDRKS TMVAQSQIGF IDFIVEPTFS LLTDSTEKIV IPLIEEASKA ETSSYVASSS TTIVGLHIAD ALRRSNTKGS MSDGSYSPDY SLAAVDLKSF KNNLVDIIQQ NKERWKELAA QGESDLHKNS EDLVNAEEKH DETHSTRTRP LEQKLISEED LAANDILDYK DDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
SDS-PAGE : |
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Gene Name : | PDE1A phosphodiesterase 1A [ Homo sapiens (human) ] |
Official Symbol : | PDE1A |
Synonyms : | PDE1A; phosphodiesterase 1A, calmodulin-dependent; calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase 1A; hCam-1; cam-PDE 1A; 61 kDa Cam-PDE; phosphodiesterase-1A; calmodulin-dependent phosphodiesterase; 3,5 cyclic nucleotide phosphodiesterase; calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase; HCAM1; HSPDE1A; MGC26303; |
Gene ID : | 5136 |
mRNA Refseq : | NM_005019 |
Protein Refseq : | NP_005010 |
MIM : | 171890 |
UniProt ID : | P54750 |
◆ Recombinant Protein
Pde1a-4742M | Recombinant Mouse Pde1a Protein, Myc/DDK-tagged | +Inquiry |
PDE1A-300H | Recombinant Human PDE1A Protein, His-tagged | +Inquiry |
PDE1A-471H | Recombinant Human PDE1A, His-tagged, Active | +Inquiry |
PDE1A-29692TH | Recombinant Human PDE1A | +Inquiry |
PDE1A-3345R | Recombinant Rhesus monkey PDE1A Protein, His-tagged | +Inquiry |
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◆ Lysates
PDE1A-3353HCL | Recombinant Human PDE1A 293 Cell Lysate | +Inquiry |
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Pde10aPDE11APDE1APDE1BPde1cPDE2APDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE6BPDE6CPDE6DPDE7APDE7BPDE8APDE9APDE4DIPPDE12PDE6APDE8BPDE6GPDE6H
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