Recombinant Human PDE1B, GST-tagged

• Cat.No.: PDE1B-442H
• Product Overview: Recombinant Human PDE1B, full length with N-terminal GST tag expressed in aBaculovirusinfected Sf9 cell expression system. MW= 87 kDa.

Specification

• Cat. No.: PDE1B-442H
• Description: Cone cGMP-specific 3",5"-cyclic phosphodiesterase 1B is an enzyme that in humans is encoded by the PDE1B gene.
• Source: Baculovirus infected Sf9 cell.
• Purity: >70%.
• Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
• Formulated In: 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 20% glycerol, and 3 mM DTT.
• Stability: >6 months at –80°C.

Gene Information

• Gene Name: PDE1B phosphodiesterase 1B, calmodulin-dependent [ Homo sapiens ]
• Synonyms: PDE1B; phosphodiesterase 1B, calmodulin-dependent; PDE1B1; PDES1B; EC 3.1.4.17; Phosphodiesterase-1B; phosphodiesterase IB, calmodulin-dependent; calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase; presumed 63kDa form of the type 1 cyclic nucleotide phosphodiesterase family known as PDE1B; Calcium/calmodulin-dependent 3",5"-cyclic nucleotide phosphodiesterase 1B; Cam-PDE 1B; 63 kDa Cam-PDE
• Gene ID: 5153
• mRNA Refseq: NM_000924
• Protein Refseq: NP_000915
• MIM: 171891
• UniProt ID: Q01064
• Chromosome Location: 12q13
• Pathway: Calcium signaling pathway; Progesterone-mediated oocyte maturation; Purine metabolism; Opioid Signalling; Opioid Signalling; Signaling by GPCR; Signalling by NGF
• Function: calmodulin binding; calmodulin-dependent cyclic-nucleotide phosphodiesterase activity; hydrolase activity