PDE1C-047H
Optional Service: Optional requirements on this protein
Product Overview :
Recombinant N-terminal His-GST-tagged full length human PDE1C1 protein (1-634) was expressed in insect cells.
Description :
This gene encodes an enzyme that belongs to the 3'5'-cyclic nucleotide phosphodiesterase family. Members of this family catalyze hydrolysis of the cyclic nucleotides, cyclic adenosine monophosphate and cyclic guanosine monophosphate, to the corresponding nucleoside 5'-monophosphates. The enzyme encoded by this gene regulates proliferation and migration of vascular smooth muscle cells, and neointimal hyperplasia. This enzyme also plays a role in pathological vascular remodeling by regulating the stability of growth factor receptors, such as PDGF-receptor-beta.
Source :
Insect cell
Species :
Human
Tag :
His/GST
Form :
Lyophilized
Molecular Mass :
100 kDa
Protein length :
1-634
Endotoxin :
<1.0 EU/ μg, determined by the LAL endotoxin assay.
Purity :
≥85% estimated by SDS-PAGE
Stability :
≥ 6 months
Storage :
At -80 centigrade.
Storage Buffer :
Sterile 20 mM Tris, 500 mM NaCl, pH 7.4, 10% glycerol, 3 mM DTT
SDS-PAGE analysis of PDE1C :
Lane 1: MW Markers Lane 2: PDE1C This protein has a calculated molecular weight of 100 kDa. It has an apparent molecular weight of approximately 97 kDa by SDS-PAGE under reducing conditions.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.