| Cat.No. : |
PDE3A-29931TH
Optional Service: Optional requirements on this protein
|
| Product Overview : |
Recombinant fragment of Human PDE3A with N-terminal proprietary tag.Mol Wt 37.51 kDa inclusive of tag. |
| Description : |
This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| Protein length : |
108 amino acids |
| Molecular Weight : |
37.510kDa inclusive of tags |
| Source : |
Wheat germ |
| Form : |
Liquid |
| Purity : |
Proprietary Purification |
| Storage buffer : |
pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris buffered saline |
| Storage : |
Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
| Sequences of amino acids : |
TPASSLVSKI SAVQFPESAD TTAKQSLGSH RALTYTQSAP DLSPQILTPP VICSSCGRPY SQGNPADEPL ERSGVATRTP SRTDDTAQVT SDYETNNNSD SSDIVQNE |
| Sequence Similarities : |
Belongs to the cyclic nucleotide phosphodiesterase family. PDE3 subfamily. |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.