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Recombinant Human PHGDH Protein, His-tagged

Cat.No. : PHGDH-477H
Product Overview : Recombinant Human PHGDH fused with His tag at N-terminal was expressed in Sf9 cells.
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  • Gene Information
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Description : THis gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in tHis gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known.
Source : Sf9 cells
Tag : His
Form : 50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol. Store at -80 centigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
Molecular Mass : 56.7 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : PHGDH phosphoglycerate dehydrogenase [ Homo sapiens ]
Official Symbol : PHGDH
Synonyms : PHGDH; phosphoglycerate dehydrogenase; D-3-phosphoglycerate dehydrogenase; PDG; PGDH; SERA; 3-phosphoglycerate dehydrogenase; PGD; PGAD; 3PGDH; 3-PGDH; MGC3017;
Gene ID : 26227
mRNA Refseq : NM_006623
Protein Refseq : NP_006614
MIM : 606879
UniProt ID : O43175

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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