Recombinant Human PI3 protein, His-tagged

• Cat.No.: PI3-02H
• Product Overview: Recombinant Human PI3 protein, fused to His-tag, was expressed in Insect cell.

Specification

• Description: This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria, and fungal pathogens. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines.
• Source: Insect cell
• Species: Human
• Tag: His
• Form: Liquid in. Phosphate-Buffered Saline (pH 7.4) 10% glycerol.
• Molecular Mass: 10.7 kDa
• Protein length: 23-117aa
• AA Sequence: AVTGVPVKGQ DTVKGRVPFN GQDPVKGQVS VKGQDKVKAQ EPVKGPVSTK PGSCPIILIR CAMLNPPNRC LKDTDCPGIK KCCEGSCGMA CFVPQHHHHH H
• Endotoxin: < 1 EU per 1ug of protein (determined by LAL method).
• Purity: > 85%
• Applications: SDS-PAGE
• Storage: Can be stored at 2 centigrade to 8 centigrade for 1 week. For long term storage, aliquot and store at -20 centigrade to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.2mg/ml

Gene Information

• Gene Name: PI3 peptidase inhibitor 3 [ Homo sapiens (human) ]
• Official Symbol: PI3
• Synonyms: Elafin preproprotein; Cementoin; ESI; SKALP; WAP3; WFDC14
• Gene ID: 5266
• mRNA Refseq: NM_002638
• Protein Refseq: NP_002629
• MIM: 182257
• UniProt ID: P19957