Recombinant Human PICK1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human PICK1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : PICK1-4327H
Product Overview : PICK1 MS Standard C13 and N15-labeled recombinant protein (NP_001034673) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : The protein encoded by this gene contains a PDZ domain, through which it interacts with protein kinase C, alpha (PRKCA). This protein may function as an adaptor that binds to and organizes the subcellular localization of a variety of membrane proteins. It has been shown to interact with multiple glutamate receptor subtypes, monoamine plasma membrane transporters, as well as non-voltage gated sodium channels, and may target PRKCA to these membrane proteins and thus regulate their distribution and function. This protein has also been found to act as an anchoring protein that specifically targets PRKCA to mitochondria in a ligand-specific manner. Three transcript variants encoding the same protein have been found for this gene.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 46.6 kDa
AA Sequence : MFADLDYDIE EDKLGIPTVP GKVTLQKDAQ NLIGISIGGG AQYCPCLYIV QVFDNTPAAL DGTVAAGDEI TGVNGRSIKG KTKVEVAKMI QEVKGEVTIH YNKLQADPKQ GMSLDIVLKK VKHRLVENMS SGTADALGLS RAILCNDGLV KRLEELERTA ELYKGMTEHT KNLLRAFYEL SQTHRAFGDV FSVIGVREPQ PAASEAFVKF ADAHRSIEKF GIRLLKTIKP MLTDLNTYLN KAIPDTRLTI KKYLDVKFEY LSYCLKVKEM DDEEYSCIAL GEPLYRVSTG NYEYRLILRC RQEARARFSQ MRKDVLEKME LLDQKHVQDI VFQLQRLVST MSKYYNDCYA VLRDADVFPI EVDLAHTTLA YGLNQEEFTD GEEEEEEEDT AAGEPSRDTR GAAGPLDKGG SWCDSTRTRP LEQKLISEED LAANDILDYK DDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : PICK1 protein interacting with PRKCA 1 [ Homo sapiens (human) ]
Official Symbol : PICK1
Synonyms : PICK1; protein interacting with PRKCA 1; PRKCABP, protein interacting with PRKCA, protein kinase C, alpha binding protein; PRKCA-binding protein; dJ1039K5; MGC15204; protein interacting with C kinase 1; protein kinase C-alpha-binding protein; PICK; PRKCABP;
Gene ID : 9463
mRNA Refseq : NM_001039584
Protein Refseq : NP_001034673
MIM : 605926
UniProt ID : Q9NRD5

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