Recombinant Human PIK3R3 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: PIK3R3-2213H
• Product Overview: PIK3R3 MS Standard C13 and N15-labeled recombinant protein (NP_001107644) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Phosphatidylinositol 3-kinase (PI3K) phosphorylates phosphatidylinositol and similar compounds, which then serve as second messengers in growth signaling pathways. PI3K is composed of a catalytic and a regulatory subunit. The protein encoded by this gene represents a regulatory subunit of PI3K. The encoded protein contains two SH2 domains through which it binds activated protein tyrosine kinases to regulate their activity.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 54.3 kDa
• AA Sequence: MYNTVWSMDRDDADWREVMMPYSTE LIFYIEMDPPALPPKPPKPMTSAVP NGMKDSSVSLQDAEWYWGDISREEV NDKLRDMPDGTFLVRDASTKMQGDY TLTLRKGGNNKLIKIYHRDGKYGFS DPLTFNSVVELINHYHHESLAQYNP KLDVKLMYPVSRYQQDQLVKEDNID AVGKKLQEYHSQYQEKSKEYDRLYE EYTRTSQEIQMKRTAIEAFNETIKI FEEQCHTQEQHSKEYIERFRREGNE KEIERIMMNYDKLKSRLGEIHDSKM RLEQDLKNQALDNREIDKKMNSIKP DLIQLRKIRDQHLVWLNHKGVRQKR LNVWLGIKNEDADENYFINEEDENL PHYDEKTWFVEDINRVQAEDLLYGK PDGAFLIRESSKKGCYACSVVADGE VKHCVIYSTARGYGFAEPYNLYSSL KELVLHYQQTSLVQHNDSLNVRLAY PVHAQMPSLCRTRTRPLEQKLISEE DLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: PIK3R3 phosphoinositide-3-kinase regulatory subunit 3 [ Homo sapiens (human) ]
• Official Symbol: PIK3R3
• Synonyms: PIK3R3; phosphoinositide-3-kinase, regulatory subunit 3 (gamma); phosphatidylinositol 3-kinase regulatory subunit gamma; p55; p55PIK; PI3-kinase subunit p55-gamma; PI3K regulatory subunit gamma; 100% homology to SWISS-PROT Q92569; PI3-kinase regulatory subunit gamma; ptdIns-3-kinase regulatory subunit gamma; ptdIns-3-kinase regulatory subunit p55-gamma; phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma); phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma; phosphoinositide-3-kinase, regulatory subunit, polypeptide 3 (p55, gamma); phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 3 (p55, gamma); p55-GAMMA; FLJ41892; DKFZp686P05226
• Gene ID: 8503
• mRNA Refseq: NM_001114172
• Protein Refseq: NP_001107644
• MIM: 606076
• UniProt ID: Q92569