Recombinant Human PKP1 Protein, Myc/DDK-tagged, C13 and N15-labeled
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Cat.No. : | PKP1-719H |
Product Overview : | PKP1 MS Standard C13 and N15-labeled recombinant protein (NP_001005337) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
Description : | This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may be involved in molecular recruitment and stabilization during desmosome formation. Mutations in this gene have been associated with the ectodermal dysplasia/skin fragility syndrome. Two transcript variants encoding different isoforms have been found for this gene. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 80.5 kDa |
AA Sequence : | MNHSPLKTAL AYECFQDQDN STLALPSDQK MKTGTSGRQR VQEQVMMTVK RQKSKSSQSS TLSHSNRGSM YDGLADNYNY GTTSRSSYYS KFQAGNGSWG YPIYNGTLKR EPDNRRFSSY SQMENWSRHY PRGSCNTTGA GSDICFMQKI KASRSEPDLY CDPRGTLRKG TLGSKGQKTT QNRYSFYSTC SGQKAIKKCP VRPPSCASKQ DPVYIPPISC NKDLSFGHSR ASSKICSEDI ECSGLTIPKA VQYLSSQDEK YQAIGAYYIQ HTCFQDESAK QQVYQLGGIC KLVDLLRSPN QNVQQAAAGA LRNLVFRSTT NKLETRRQNG IREAVSLLRR TGNAEIQKQL TGLLWNLSST DELKEELIAD ALPVLADRVI IPFSGWCDGN SNMSREVVDP EVFFNATGCL RNLSSADAGR QTMRNYSGLI DSLMAYVQNC VAASRCDDKS VENCMCVLHN LSYRLDAEVP TRYRQLEYNA RNAYTEKSST GCFSNKSDKM MNNNYDCPLP EEETNPKGSG WLYHSDAIRT YLNLMGKSKK DATLEACAGA LQNLTASKGL MSSGMSQLIG LKEKGLPQIA RLLQSGNSDV VRSGASLLSN MSRHPLLHRV MGNQVFPEVT RLLTSHTGNT SNSEDILSSA CYTVRNLMAS QPQLAKQYFS SSMLNNIINL CRSSASPKAA EAARLLLSDM WSSKELQGVL RQQGFDRNML GTLAGANSLR NFTSRFTRTR PLEQKLISEE DLAANDILDY KDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
SDS-PAGE : |
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Gene Name : | PKP1 plakophilin 1 [ Homo sapiens (human) ] |
Official Symbol : | PKP1 |
Synonyms : | PKP1; plakophilin 1 (ectodermal dysplasia/skin fragility syndrome); plakophilin-1; B6P; band 6 protein; MGC138829; |
Gene ID : | 5317 |
mRNA Refseq : | NM_001005337 |
Protein Refseq : | NP_001005337 |
MIM : | 601975 |
UniProt ID : | Q13835 |
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◆ Lysates
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