Recombinant Human PLA2G3 Protein, His-tagged

• Cat.No.: PLA2G3-118H
• Product Overview: Recombinant Human PLA2G3 fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: This gene encodes a protein that belongs to the secreted phospholipase A2 family, whose members include the bee venom enzyme. The encoded enzyme functions in lipid metabolism and catalyzes the calcium-dependent hydrolysis of the sn-2 acyl bond of phospholipids to release arachidonic acid and lysophospholipids. This enzyme acts as a negative regulator of ciliogenesis, and may play a role in cancer development by stimulating tumor cell growth and angiogenesis. This gene is associated with oxidative stress, and polymorphisms in this gene are linked to risk for Alzheimer's disease.
• Source: E. coli
• Species: Human
• Tag: His
• Form: 50mM Tris, 8M Urea, pH8.0.
• Molecular Mass: 57 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: PLA2G3 phospholipase A2, group III [ Homo sapiens ]
• Official Symbol: PLA2G3
• Synonyms: PLA2G3; phospholipase A2, group III; group 3 secretory phospholipase A2; GIII SPLA2; sPLA2-III; GIII sPLA2; group III secreted phospholipase A2; group III secretory phospholipase A2; phosphatidylcholine 2-acylhydrolase 3; phosphatidylcholine 2-acylhydrolase GIII; SPLA2III; GIII-SPLA2
• Gene ID: 50487
• mRNA Refseq: NM_015715
• Protein Refseq: NP_056530
• MIM: 611651
• UniProt ID: Q9NZ20