Recombinant Human PLAA Protein (Glu162-Ala312), His tagged

• Cat.No.: PLAA-5326H
• Product Overview: Recombinant human PLAA (Glu162-Ala312) fused with His tag was expressed in E. coli.

Specification

• Description: Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and is overexpressed on many cancer cells, dephosphorylate the d-tyrosine phosphates on the surface of the magnetic nanoparticle and enable the magnetic nanoparticles to adhere selectively to the cancer cells, such as HeLa cells. Placental alkaline phosphatase (PLAP), encoded by the ALPP gene, is produced by the fetal side of the placenta.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 17.61 kDa
• Protein Length: Glu162-Ala312
• Purity: >90% as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS, pH 7.5 or lyophilized from PBS, pH 7.5.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: PLAA phospholipase A2-activating protein [ Homo sapiens (human) ]
• Official Symbol: PLAA
• Synonyms: PLAA; phospholipase A2-activating protein; phospholipase A-2-activating protein; DOA1; DOA1 homolog (S. cerevisiae); FLJ11281; FLJ12699; PLA2P; PLAP; DOA1 homolog; phospholipase A2 activating protein
• Gene ID: 9373
• mRNA Refseq: NM_001031689
• Protein Refseq: NP_001026859
• MIM: 603873
• UniProt ID: Q9Y263