Recombinant Human PLAUR Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human PLAUR Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : PLAUR-3942H
Product Overview : PLAUR MS Standard C13 and N15-labeled recombinant protein (NP_002650) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 37 kDa
AA Sequence : MGHPPLLPLL LLLHTCVPAS WGLRCMQCKT NGDCRVEECA LGQDLCRTTI VRLWEEGEEL ELVEKSCTHS EKTNRTLSYR TGLKITSLTE VVCGLDLCNQ GNSGRAVTYS RSRYLECISC GSSDMSCERG RHQSLQCRSP EEQCLDVVTH WIQEGEEGRP KDDRHLRGCG YLPGCPGSNG FHNNDTFHFL KCCNTTKCNE GPILELENLP QNGRQCYSCK GNSTHGCSSE ETFLIDCRGP MNQCLVATGT HEPKNQSYMV RGCATASMCQ HAHLGDAFSM NHIDVSCCTK SGCNHPDLDV QYRSGAAPQP GPAHLSLTIT LLMTARLWGG TLLWTTRTRP LEQKLISEED LAANDILDYK DDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : PLAUR plasminogen activator, urokinase receptor [ Homo sapiens (human) ]
Official Symbol : PLAUR
Synonyms : PLAUR; plasminogen activator, urokinase receptor; urokinase plasminogen activator surface receptor; CD87; UPAR; URKR; urokinase type plasminogen activator (uPA) receptor; monocyte activation antigen Mo3; u-plasminogen activator receptor form 2; urokinase-type plasminogen activator (uPA) receptor; U-PAR;
Gene ID : 5329
mRNA Refseq : NM_002659
Protein Refseq : NP_002650
MIM : 173391
UniProt ID : Q03405

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