Recombinant Human PLXNA1 Protein, MYC/DDK-tagged

• Cat.No.: PLXNA1-509H
• Product Overview: Recombinant Human PLXNA1 fused with MYC/DDK tag at C-terminal was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. The encoded protein is capable of glycosylating fibronectin peptide in vitro and is expressed in a fibroblast cell line, indicating that it may be involved in the synthesis of oncofetal fibronectin.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 210.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Notes: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: PLXNA1 plexin A1 [ Homo sapiens ]
• Official Symbol: PLXNA1
• Synonyms: PLXNA1; plexin A1; PLXN1; plexin-A1; NOV; plexin 1; semaphorin receptor NOV; NOVP; PLEXIN-A1; DKFZp761P19121
• Gene ID: 5361
• mRNA Refseq: NM_032242
• Protein Refseq: NP_115618
• MIM: 601055
• UniProt ID: Q9UIW2