Recombinant Mouse Plxna1 Protein, Myc/DDK-tagged

• Cat.No.: Plxna1-4948M
• Product Overview: Purified recombinant protein of mouse full-length plexin A1 (Plxna1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.
• Molecular Mass: 211.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Plxna1 plexin A1 [ Mus musculus (house mouse) ]
• Official Symbol: Plxna1
• Synonyms: PLXNA1; plexin A1; plexin-A1; plex 1; plexin 1; plexin-1; NOV; Plxn1; PlexA1; mKIAA4053; 2600013D04Rik; KIAA4053
• Gene ID: 18844
• mRNA Refseq: NM_008881
• Protein Refseq: NP_032907
• UniProt ID: P70206