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Recombinant Human PMAIP1 Protein, Myc/DDK-tagged, C13 and N15-labeled
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Cat.No. : | PMAIP1-3049H |
Product Overview : | PMAIP1 MS Standard C13 and N15-labeled recombinant protein (NP_066950) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
Description : | Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1. Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 5.8 kDa |
AA Sequence : | MPGKKARKNA QPSPARAPAE LEVECATQLR RFGDKLNFRQ KLLNLISKLF CSGTTRTRPL EQKLISEEDL AANDILDYKD DDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
SDS-PAGE : |
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Gene Name : | PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 [ Homo sapiens (human) ] |
Official Symbol : | PMAIP1 |
Synonyms : | PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1; APR; NOXA; protein Noxa; PMA-induced protein 1; immediate-early-response protein APR; adult T cell leukemia-derived PMA-responsive; |
Gene ID : | 5366 |
mRNA Refseq : | NM_021127 |
Protein Refseq : | NP_066950 |
MIM : | 604959 |
UniProt ID : | Q13794 |
◆ Recombinant Protein
Pmaip1-4951M | Recombinant Mouse Pmaip1 Protein, Myc/DDK-tagged | +Inquiry |
PMAIP1-1803H | Recombinant Human PMAIP1, His-tagged | +Inquiry |
PMAIP1-13007M | Recombinant Mouse PMAIP1 Protein | +Inquiry |
PMAIP1-4539R | Recombinant Rat PMAIP1 Protein | +Inquiry |
PMAIP1-3482R | Recombinant Rhesus monkey PMAIP1 Protein, His-tagged | +Inquiry |
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◆ Lysates
PMAIP1-3090HCL | Recombinant Human PMAIP1 293 Cell Lysate | +Inquiry |
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