Recombinant Human PMAIP1 Protein, Myc/DDK-tagged, C13 and N15-labeled PMAIP1-3049H

Recombinant Human PMAIP1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. :	PMAIP1-3049H
Product Overview :	PMAIP1 MS Standard C13 and N15-labeled recombinant protein (NP_066950) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description :	Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1. Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.
Source :	HEK293
Species :	Human
Tag :	Myc/DDK
Molecular Mass :	5.8 kDa
AA Sequence :	MPGKKARKNA QPSPARAPAE LEVECATQLR RFGDKLNFRQ KLLNLISKLF CSGTTRTRPL EQKLISEEDL AANDILDYKD DDDKV
Purity :	> 80% as determined by SDS-PAGE and Coomassie blue staining
Stability :	Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage :	Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration :	50 μg/mL as determined by BCA
Storage Buffer :	100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name :	PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 [ Homo sapiens (human) ]
Official Symbol :	PMAIP1
Synonyms :	PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1; APR; NOXA; protein Noxa; PMA-induced protein 1; immediate-early-response protein APR; adult T cell leukemia-derived PMA-responsive;
Gene ID :	5366
mRNA Refseq :	NM_021127
Protein Refseq :	NP_066950
MIM :	604959
UniProt ID :	Q13794