Recombinant Human PNKP Protein (1-521 aa), His-SUMO-tagged
Cat.No. : | PNKP-1109H |
Product Overview : | Recombinant Human PNKP Protein (1-521 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Research Area: Epigenetics and Nuclear Signaling. Protein Description: Full Length. |
- Specification
- Gene Information
- Related Products
Description : | Plays a key role in the repair of DNA damage, functioning as part of both the non-homologous end-joining (NHEJ) and base excision repair (BER) pathways. Through its two catalytic activities, PNK ensures that DNA termini are compatible with extension and ligation by either roving 3'-phosphates from, or by phosphorylating 5'-hydroxyl groups on, the ribose sugar of the DNA backbone. |
Source : | E. coli |
Species : | Human |
Tag : | His-SUMO |
Form : | Tris-based buffer, 50% glycerol |
Molecular Mass : | 73.1 kDa |
Protein length : | 1-521 aa |
AA Sequence : | MGEVEAPGRLWLESPPGGAPPIFLP SDGQALVLGRGPLTQVTDRKCSRTQ VELVADPETRTVAVKQLGVNPSTTG TQELKPGLEGSLGVGDTLYLVNGLH PLTLRWEETRTPESQPDTPPGTPLV SQDEKRDAELPKKRMRKSNPGWENL EKLLVFTAAGVKPQGKVAGFDLDGT LITTRSGKVFPTGPSDWRILYPEIP RKLRELEAEGYKLVIFTNQMSIGRG KLPAEEFKAKVEAVVEKLGVPFQVL VATHAGLYRKPVTGMWDHLQEQAND GTPISIGDSIFVGDAAGRPANWAPG RKKKDFSCADRLFALNLGLPFATPE EFFLKWPAAGFELPAFDPRTVSRSG PLCLPESRALLSASPEVVVAVGFPG AGKSTFLKKHLVSAGYVHVNRDTLG SWQRCVTTCETALKQGKRVAIDNTN PDAASRARYVQCARAAGVPCRCFLF TATLEQARHNNRFREMTDSSHIPVS DMVMYGYRKQFEAPTLAEGFSAILE IPFRLWVEPRLGRLYCQFSEG |
Purity : | > 90% as determined by SDS-PAGE. |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
Concentration : | A hardcopy of COA with concentration instruction is sent along with the products. |
Gene Name : | PNKP polynucleotide kinase 3-phosphatase [ Homo sapiens ] |
Official Symbol : | PNKP |
Synonyms : | PNKP; PNK; MCSZ; EIEE10; |
Gene ID : | 11284 |
mRNA Refseq : | NM_007254 |
Protein Refseq : | NP_009185 |
MIM : | 605610 |
UniProt ID : | Q96T60 |
Products Types
◆ Recombinant Protein | ||
PNKP-2145H | Recombinant Human PNKP Protein, MYC/DDK-tagged | +Inquiry |
Pnkp-4963M | Recombinant Mouse Pnkp Protein, Myc/DDK-tagged | +Inquiry |
PNKP-4787Z | Recombinant Zebrafish PNKP | +Inquiry |
PNKP-3964H | Recombinant Human PNKP protein, His-tagged | +Inquiry |
◆ Lysates | ||
PNKP-1385HCL | Recombinant Human PNKP cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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