Recombinant Human POFUT2 protein, MYC/DDK-tagged

• Cat.No.: POFUT2-3892H
• Product Overview: Recombinant Human POFUT2, transcript variant 3, fused with MYC/DDK tag at C-terminal was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: Fucose is typically found as a terminal modification of branched chain glycoconjugates, but it also exists in direct O-linkage to serine or threonine residues within cystine knot motifs in epidermal growth factor (EGF; MIM 131530)-like repeats or thrombospondin (THBS; see MIM 188060) type-1 repeats. POFUT2 is an O-fucosyltransferase that use THBS type-1 repeats as substrates (Luo et al., 2006 [PubMed 16464857]).
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 49.8 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: POFUT2 protein O-fucosyltransferase 2 [ Homo sapiens ]
• Official Symbol: POFUT2
• Synonyms: POFUT2; protein O-fucosyltransferase 2; C21orf80, chromosome 21 open reading frame 80; GDP-fucose protein O-fucosyltransferase 2; FUT13; KIAA0958; O-FucT-2; peptide-O-fucosyltransferase 2; C21orf80
• Gene ID: 23275
• mRNA Refseq: NM_133635
• Protein Refseq: NP_598368
• MIM: 610249
• UniProt ID: Q9Y2G5
• Chromosome Location: 21q22.3
• Pathway: Other types of O-glycan biosynthesis, organism-specific biosystem; Other types of O-glycan biosynthesis, conserved biosystem
• Function: peptide-O-fucosyltransferase activity; transferase activity, transferring glycosyl groups