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Recombinant Human POLD2 Protein, His-tagged

Cat.No. : POLD2-111H
Product Overview : Recombinant Human POLD2, transcript variant 2, fused with His tag at C-terminal was expressed in E. coli.
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  • Gene Information
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Description : This gene encodes the 50-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein is required for the stimulation of DNA polymerase delta activity by the processivity cofactor proliferating cell nuclear antigen (PCNA). Expression of this gene may be a marker for ovarian carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5.
Source : E. coli
Species : Human
Tag : His
Form : Supplied as a 0.2 µM filtered solution of PBS, 10% Glycerol, pH 7.4
Molecular Mass : 52.3kD
AA Sequence : MFSEQAAQRAHTLLSPPSANNATFA RVPVATYTNSSQPFRLGERSFSRQY AHIYATRLIQMRPFLENRAQQHWGS GVGVKKLCELQPEEKCCVVGTLFKA MPLQPSILREVSEEHNLLPQPPRSK YIHPDDELVLEDELQRIKLKGTIDV SKLVTGTVLAVFGSVRDDGKFLVED YCFADLAPQKPAPPLDTDRFVLLVS GLGLGGGGGESLLGTQLLVDVVTGQ LGDEGEQCSAAHVSRVILAGNLLSH STQSR
Endotoxin : Endotoxin level is <0.1 ng/µg of protein (<1EU/µg).
Purity : >95% as determined by SDS-PAGE and Coomassie blue staining
Gene Name : POLD2 polymerase (DNA directed), delta 2, regulatory subunit 50kDa [ Homo sapiens ]
Official Symbol : POLD2
Synonyms : POLD2; polymerase (DNA directed), delta 2, regulatory subunit 50kDa; polymerase (DNA directed), delta 2, regulatory subunit (50kD); DNA polymerase delta subunit 2; DNA polymerase delta subunit p50;
Gene ID : 5425
mRNA Refseq : NM_006230
Protein Refseq : NP_006221
MIM : 600815
UniProt ID : P49005

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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