Recombinant Human POLK Protein, Myc/DDK-tagged, C13 and N15-labeled
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| Cat.No. : | POLK-4176H |
| Product Overview : | POLK MS Standard C13 and N15-labeled recombinant protein (NP_057302) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
| Description : | This gene encodes a member of the DNA polymerase type-Y family of proteins. The encoded protein is a specialized DNA polymerase that catalyzes translesion DNA synthesis, which allows DNA replication in the presence of DNA lesions. Human cell lines lacking a functional copy of this gene exhibit impaired genome integrity and enhanced susceptibility to oxidative damage. Mutations in this gene that impair enzyme activity may be associated with prostate cancer in human patients. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | Myc/DDK |
| Molecular Mass : | 98.6 kDa |
| AA Sequence : | MDSTKEKCDS YKDDLLLRMG LNDNKAGMEG LDKEKINKII MEATKGSRFY GNELKKEKQV NQRIENMMQQ KAQITSQQLR KAQLQVDRFA MELEQSRNLS NTIVHIDMDA FYAAVEMRDN PELKDKPIAV GSMSMLSTSN YHARRFGVRA AMPGFIAKRL CPQLIIVPPN FDKYRAVSKE VKEILADYDP NFMAMSLDEA YLNITKHLEE RQNWPEDKRR YFIKMGSSVE NDNPGKEVNK LSEHERSISP LLFEESPSDV QPPGDPFQVN FEEQNNPQIL QNSVVFGTSA QEVVKEIRFR IEQKTTLTAS AGIAPNTMLA KVCSDKNKPN GQYQILPNRQ AVMDFIKDLP IRKVSGIGKV TEKMLKALGI ITCTELYQQR ALLSLLFSET SWHYFLHISL GLGSTHLTRD GERKSMSVER TFSEINKAEE QYSLCQELCS ELAQDLQKER LKGRTVTIKL KNVNFEVKTR ASTVSSVVST AEEIFAIAKE LLKTEIDADF PHPLRLRLMG VRISSFPNEE DRKHQQRSII GFLQAGNQAL SATECTLEKT DKDKFVKPLE MSHKKSFFDK KRSERKWSHQ DTFKCEAVNK QSFQTSQPFQ VLKKKMNENL EISENSDDCQ ILTCPVCFRA QGCISLEALN KHVDECLDGP SISENFKMFS CSHVSATKVN KKENVPASSL CEKQDYEAHP KIKEISSVDC IALVDTIDNS SKAESIDALS NKHSKEECSS LPSKSFNIEH CHQNSSSTVS LENEDVGSFR QEYRQPYLCE VKTGQALVCP VCNVEQKTSD LTLFNVHVDV CLNKSFIQEL RKDKFNPVNQ PKESSRSTGS SSGVQKAVTR TKRPGLMTKY STSKKIKPNN PKHTLDIFFK TRTRPLEQKL ISEEDLAAND ILDYKDDDDK V |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : | 50 μg/mL as determined by BCA |
| Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
| SDS-PAGE : |
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| Gene Name : | POLK DNA polymerase kappa [ Homo sapiens (human) ] |
| Official Symbol : | POLK |
| Synonyms : | POLK; polymerase (DNA directed) kappa; DINB1; DNA polymerase kappa; DINB protein; DINP; POLQ; |
| Gene ID : | 51426 |
| mRNA Refseq : | NM_016218 |
| Protein Refseq : | NP_057302 |
| MIM : | 605650 |
| UniProt ID : | Q9UBT6 |
◆ Recombinant Protein
| Polk-4991M | Recombinant Mouse Polk Protein, Myc/DDK-tagged | +Inquiry |
| POLK-763H | Recombinant Human POLK Protein, His-tagged | +Inquiry |
| POLK-1835H | Recombinant Human POLK, GST-tagged | +Inquiry |
| POLK-837H | Recombinant Human POLK, MYC/DDK-tagged | +Inquiry |
| POLK-765H | Recombinant Human POLK, GST-tagged | +Inquiry |
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◆ Lysates
| POLK-3045HCL | Recombinant Human POLK 293 Cell Lysate | +Inquiry |
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