Recombinant Human Poly (ADP-ribose) Polymerase 2, GST-tagged
| Cat.No. : | PARP2-433H |
| Product Overview : | Recombinant Human PARP2, amino-acids 2-583 with N-terminal GST tag expressed in aBaculovirusinfected Sf9 cell expression system. MW = 92kDa. |
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| Species : | Human |
| Source : | Sf9 Cells |
| Tag : | GST |
| Protein Length : | 2-583 a.a. |
| Description : | Poly (ADP-ribose) polymerase (PARP) is a protein involved in a number of cellular processes involving mainly DNA repair and programmed cell death. |
| Purity : | >80%. |
| Application : | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
| Formulated In : | 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 30% glycerol, and 3 mM DTT. |
| Stability : | >6 months at –80°C. |
| Gene Name | PARP2 poly (ADP-ribose) polymerase 2 [ Homo sapiens ] |
| Synonyms | PARP2; poly (ADP-ribose) polymerase 2; ADP-ribosyltransferase (NAD+; poly(ADP-ribose) polymerase)-like 2; poly (ADP-ribose) polymerase family, member 2; poly (ADP-ribosyl) transferase-like 2; poly(ADP-ribose) synthetase; EC 2.4.2.30; ADPRT2; PARP-2; ADPRTL2; ADPRTL3; pADPRT-2 |
| Gene ID | 10038 |
| mRNA Refseq | NM_001042618 |
| Protein Refseq | NP_001036083 |
| MIM | 607725 |
| UniProt ID | Q9UGN5 |
| Chromosome Location | 14q11.2-q12 |
| Pathway | Base excision repair |
| Function | DNA binding; NAD or NADH binding; NAD+ ADP-ribosyltransferase activity; identical protein binding; protein N-terminus binding; transcription factor binding; transferase activity, transferring glycosyl groups; zinc ion binding |
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Not For Human Consumption!
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