| Description : |
This gene encodes a secreted extracellular matrix protein that functions in tissue development and regeneration, including wound healing, and ventricular remodeling following myocardial infarction. The encoded protein binds to integrins to support adhesion and migration of epithelial cells. This protein plays a role in cancer stem cell maintenance and metastasis. Mice lacking this gene exhibit cardiac valve disease, and skeletal and dental defects. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
87.1 kDa |
| AA Sequence : |
MIPFLPMFSLLLLLIVNPINANNHY DKILAHSRIRGRDQGPNVCALQQIL GTKKKYFSTCKNWYKKSICGQKTTV LYECCPGYMRMEGMKGCPAVLPIDH VYGTLGIVGATTTQRYSDASKLREE IEGKGSFTYFAPSNEAWDNLDSDIR RGLESNVNVELLNALHSHMINKRML TKDLKNGMIIPSMYNNLGLFINHYP NGVVTVNCARIIHGNQIATNGVVHV IDRVLTQIGTSIQDFIEAEDDLSSF RAAAITSDILEALGRDGHFTLFAPT NEAFEKLPRGVLERIMGDKVASEAL MKYHILNTLQCSESIMGGAVFETLE GNTIEIGCDGDSITVNGIKMVNKKD IVTNNGVIHLIDQVLIPDSAKQVIE LAGKQQTTFTDLVAQLGLASALRPD GEYTLLAPVNNAFSDDTLSMDQRLL KLILQNHILKVKVGLNELYNGQILE TIGGKQLRVFVYRTAVCIENSCMEK GSKQGRNGAIHIFREIIKPAEKSLH EKLKQDKRFSTFLSLLEAADLKELL TQPGDWTLFVPTNDAFKGMTSEEKE ILIRDKNALQNIILYHLTPGVFIGK GFEPGVTNILKTTQGSKIFLKEVND TLLVNELKSKESDIMTTNGVIHVVD KLLYPADTPVGNDQLLEILNKLIKY IQIKFVRGSTFKEIPVTVYRPTLTK VKIEGEPEFRLIKEGETITEVIHGE PIIKKYTKIIDGVPVEITEKETREE RIITGPEIKYTRISTGGGETEETLK KLLQEDTPVRKLQANKKVQGSRRRL REGRSQTRTRPLEQKLISEEDLAAN DILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
