| Description : |
This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. |
| Source : |
Wheat Germ |
| Species : |
Human |
| Tag : |
GST |
| Form : |
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
| Molecular Mass : |
97.8 kDa |
| Protein length : |
1-634 a.a. |
| AA Sequence : |
MSLVPATNYIYTPLNQLKGGTIVNV YGVVKFFKPPYLSKGTDYCSVVTIV DQTNVKLTCLLFSGNYEALPIIYKN GDIVRFHRLKIQVYKKETQGITSSG FASLTFEGTLGAPIIPRTSSKYFNF TTEDHKMVEALRVWASTHMSPSWTL LKLCDVQPMQYFDLTCQLLGKAEVD GASFLLKVWDGTRTPFPSWRVLIQD LVLEGDLSHIHRLQNLTIDILVYDN HVHVARSLKVGSFLRIYSLHTKLQS MNSENQTMLSLEFHLHGGTSYGRGI RVLPESNSDVDQLKKDLESANLTAN QHSDVICQSEPDDSFPSSGSVSLYE VERCQQLSATILTDHQYLERTPLCA ILKQKAPQQYRIRAKLRSYKPRRLF QSVKLHCPKCHLLQEVPHEGDLDII FQDGATKTPDVKLQNTSLYDSKIWT TKNQKGRKVAVHFAKNNGILPLSNE CLLLIEGGTLSEICKLSNKFNSVIP VRSGHEDLELLDLSAPFLIQGTIHH YGCKQCSSLRSIQNLNSLVDKTSWI PSSVAEALGIVPLQYVFVMTFTLDD GTGVLEAYLMDSDKFFQIPASEVLM DDDLQKSVDMIMDMFCPPGIKIDAY PWLECFIKSYNVTNGTDNQICYQIF DTTVAEDVI |
| Applications : |
Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
| Notes : |
Best use within three months from the date of receipt of this protein. |
| Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
