| Description : |
The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. Alternatively spliced transcript variants encoding distinct isoforms have been described. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
133.8 kDa |
| AA Sequence : |
MMCEVMPTISEAEGPPGGGGGHGSG SPSQPDADSHFEQLMVSMLEERDRL LDTLRETQETLALTQGKLHEVGHER DSLQRQLNTALPQEFAALTKELNVC REQLLEREEEIAELKAERNNTRLLL EHLECLVSRHERSLRMTVVKRQAQS PAGVSSEVEVLKALKSLFEHHKALD EKVRERLRVALERCSLLEEELGATH KELMILKEQNNQKKTLTDGVLDINH EQENTPSTSGKRSSDGSLSHEEDLA KVIELQEIISKQSREQSQMKERLAS LSSHVTELEEDLDTARKDLIKSEEM NTKLQRDVREAMAQKEDMEERITTL EKRYLAAQREATSVHDLNDKLENEI ANKDSMHRQTEDKNRQLQERLELAE QKLQQTLRKAETLPEVEAELAQRVA ALSKAEERHGNIEERLRQMEAQLEE KNQELQRARQREKMNEEHNKRLSDT VDKLLSESNERLQLHLKERMAALED KNSLLREVESAKKQLEETQHDKDQL VLNIEALRAELDHMRLRGASLHHGR PHLGSVPDFRFPMADGHTDSYSTSA VLRRPQKGRLAALRDEPSKVQTLNE QDWERAQQASVLANVAQAFESDADV SDGEDDRDTLLSSVDLLSPSGQADA HTLAMMLQEQLDAINKEIRLIQEEK ENTEQRAEEIESRVGSGSLDNLGRF RSMSSIPPYPASSLASSSPPGSGRS TPRRIPHSPAREVDRLGVMTLLPPS REEVRDDKTTIKCETSPPSSPRALR LDRLHKGALHTVSHEDIRDIRNSTG SQDGPVSNPSSSNSSQDSLHKAPKK KGIKSSIGRLFGKKEKGRPGQTGKE ALGQAGVSETDNSSQDALGLSKLGG QAEKNRKLQKKHELLEEARRQGLPF AQWDGPTVVVWLELWVGMPAWYVAA CRANVKSGAIMSALSDTEIQREIGI SNPLHRLKLRLAIQEIMSLTSPSAP PTSRTTLAYGDMNHEWIGNEWLPSL GLPQYRSYFMECLVDARMLDHLTKK DLRGQLKMVDSFHRNSFQCGIMCLR RLNYDRKELERKREESQSEIKDVLV WSNDRVIRWILSIGLKEYANNLIES GVHGALLALDETFDFSALALLLQIP TQNTQARAVLEREFNNLLVMGTDRR FDEDDDKSFRRAPSWRKKFRPKDIR GLAAGSAETLPANFRVTSSMSSPSM QPKKMQMDGMTRTRPLEQKLISEED LAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
