Recombinant Human PPFIBP1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human PPFIBP1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : PPFIBP1-4040H
Product Overview : PPFIBP1 MS Standard C13 and N15-labeled recombinant protein (NP_003613) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 113 kDa
AA Sequence : MMSDASDMLA AALEQMDGII AGSKALEYSN GIFDCQSPTS PFMGSLRALH LVEDLRGLLE MMETDEKEGL RCQIPDSTAE TLVEWLQSQM TNGHLPGNGD VYQERLARLE NDKESLVLQV SVLTDQVEAQ GEKIRDLEFC LEEHREKLNA TEEMLQQELL SRTSLETQKL DLMAEISNLK LKLTAVEKDR LDYEDKFRDT EGLIQEINDL RLKVSEMDSE RLQYEKKLKS TKDELASLKE QLEEKESEVK RLQEKLVCKM KGEGVEIVDR DENFKKKLKE KNIEVQKMKK AVESLMAANE EKDRKIEDLR QCLNRYKKMQ DTVVLAQGKK GKDGEYEELL NSSSISSLLD AQGFSDLEKS PSPTPVMGSP SCDPFNTSVP EEFHTTILQV SIPSLLPATV SMETSEKSKL TPKPETSFEE NDGNIILGAT VDTQLCDKLL TSSLQKSSSL GNLKKETSDG EKETIQKTSE DRAPAESRPF GTLPPRPPGQ DTSMDDNPFG TRKVRSSFGR GFFKIKSNKR TASAPNLDRK RSASAPTLAE TEKETAEHLD LAGASSRPKD SQRNSPFQIP PPSPDSKKKS RGIMKLFGKL RRSQSTTFNP DDMSEPEFKR GGTRATAGPR LGWSRDLGQS NSDLDMPFAK WTKEQVCNWL MEQGLGSYLN SGKHWIASGQ TLLQASQQDL EKELGIKHSL HRKKLQLALQ ALGSEEETNH GKLDFNWVTR WLDDIGLPQY KTQFDEGRVD GRMLHYMTVD DLLSLKVVSV LHHLSIKRAI QVLRINNFEP NCLRRRPSDE NTIAPSEVQK WTNHRVMEWL RSVDLAEYAP NLRGSGVHGG LMVLEPRFNV ETMAQLLNIP PNKTLLRRHL ATHFNLLIGA EAQHQKRDAM ELPDYVLLTA TAKVKPKKLA FSNFGNLRKK KQEDGEEYVC PMELGQASGS ASKKGFKPGL DMHLYEEDDL DRLEQMEDSE GTVRQIGAFS EGINNLTHML KEDDMFKDFA ARSPSASITD EDSNVTRTRP LEQKLISEED LAANDILDYK DDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : PPFIBP1 PPFIA binding protein 1 [ Homo sapiens (human) ]
Official Symbol : PPFIBP1
Synonyms : PPFIBP1; PTPRF interacting protein, binding protein 1 (liprin beta 1); liprin-beta-1; hSGT2; hSgt2p; L2; SGT2; liprin-beta 1; liprin related protein; PTPRF-interacting protein-binding protein 1; protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1; protein-tyrosine phosphatase receptor-type f polypeptide-interacting protein-binding protein 1;
Gene ID : 8496
mRNA Refseq : NM_003622
Protein Refseq : NP_003613
MIM : 603141
UniProt ID : Q86W92

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