Recombinant Human PPOX Protein, DYKDDDDK-tagged

• Cat.No.: PPOX-01H
• Product Overview: Recombinant protein from the full-length sequence of Homo sapiens protoporphyrinogen oxidase (PPOX), transcript variant 1 (NM_000309), with a DYKDDDDK tag was expressed in human cells.

Specification

• Species: Human
• Source: Human Cells
• Description: This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.
• Molecular Mass: 50.6 kDa
• Endotoxin: < 0.1 ng/μg of protein (< 1 EU/μg)
• Purity: > 90% by SDS-PAGE gel and Coomassie Blue staining
• Applications: Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
• Storage Buffer: Purified protein formulated in a sterile solution of TBS buffer, pH 7.4, without any preservatives

Gene Information

• Gene Name: PPOX protoporphyrinogen oxidase [ Homo sapiens (human) ]
• Official Symbol: PPOX
• Synonyms: PPOX; protoporphyrinogen oxidase; VP; PPO; V290M; protoporphyrinogen oxidase; EC 1.3.3.4
• Gene ID: 5498
• mRNA Refseq: NM_000309
• Protein Refseq: NP_000300
• MIM: 600923
• UniProt ID: P50336