Recombinant Human PPP1R1A Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: PPP1R1A-3204H
• Product Overview: PPP1R1A MS Standard C13 and N15-labeled recombinant protein (NP_006732) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.
• Molecular Mass: 18.9 kDa
• AA Sequence: MEQDNSPQKIQFTVPLLEPHLDPEAAEQIRRRRPTPATLVLTSDQSSPEIDEDRIPNPHLKSTLAMSPRQRKKMTRITPTMKELQMMVEHHLGQQQQGEEPEGAAESTGTQESRPPGIPDTEVESRLGTSGTAKKTAECIPKTHERGSKEPSTKEPSTHIPPLDSKGANSVTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: PPP1R1A protein phosphatase 1 regulatory inhibitor subunit 1A [ Homo sapiens (human) ]
• Official Symbol: PPP1R1A
• Synonyms: PPP1R1A; protein phosphatase 1, regulatory (inhibitor) subunit 1A; protein phosphatase 1 regulatory subunit 1A; I-1; IPP-1; inhibitor-1; protein phosphatase inhibitor 1; protein phosphatase inhibitor-1; I1; IPP1
• Gene ID: 5502
• mRNA Refseq: NM_006741
• Protein Refseq: NP_006732
• MIM: 613246
• UniProt ID: Q13522