Recombinant Human PRDM2 protein, GST-tagged

• Cat.No.: PRDM2-196H
• Product Overview: Recombinant Human PRDM2(1-340 aa) fused with GST tag at N-terminal was expressed in Insect cells.

Specification

• Description: PRDM2 is a histone methyltransferase that specifically methylates lysine-9 of histone H3. PRDM2 is a retinoblastoma protein-interacting zinc finger protein and a tumor suppressor. Loss of PRDM2 activity through loss of mRNA expression, frameshift, deletion, and missense mutation is commonly found in many types of human cancers.
• Source: Insect cells
• Species: Human
• Tag: GST
• Form: 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
• Molecular Mass: 80 kDa
• Purity: >85%
• Applications: Methyltransferase Assay
• Stability: 1 year at -70 centigrade from the date of shipment
• Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.1μg/μl

Gene Information

• Gene Name: PRDM2 PR domain containing 2, with ZNF domain [ Homo sapiens ]
• Official Symbol: PRDM2
• Gene ID: 7799
• mRNA Refseq: NM_012231
• Protein Refseq: NP_036363
• MIM: 601196
• UniProt ID: Q13029
• Chromosome Location: 1p36
• Function: DNA binding; histone-lysine N-methyltransferase activity; metal ion binding; methyltransferase activity; sequence-specific DNA binding transcription factor activity; transferase activity; zinc ion binding; zinc ion binding