Recombinant Human Prion Protein, His-tagged

• Cat.No.: PRNP-789H
• Product Overview: Recombinant Human Prion Protein (globular domain/residues 90-231) was expressed in E. coli with His tag.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 90-231 a.a.
• Description: N-terminal His-tagged prion protein globular domain (amino acid residues 90-231). The protein may be reconstituted in detergent-containing buffers e.g. TX-100 (0.5%) or under mild denaturing conditions (e.g. 1.5 M guanidine-HCl or urea). The His-tagged PrPc is an ideal positive control in immunochemical detection of prions. It may be used directly for the production of antibodies in animals.
• Molecular Mass: 18.5 kDa
• Purity: > 90 % (SDS-PAGE)
• Storage: Store at -80 centigrade, avoid freeze/thaw cycles.

Gene Information

• Gene Name: PRNP prion protein [ Homo sapiens ]
• Official Symbol: PRNP
• Synonyms: CJD; GSS; PrP; ASCR; KURU; PRIP; PrPc; CD230; AltPrP; p27-30; PrP27-30; PrP33-35C
• Gene ID: 5621
• mRNA Refseq: NM_000311.3
• Protein Refseq: NP_000302.1
• MIM: 176640
• UniProt ID: O75942