Recombinant Human PRKAA1 Protein, MYC/DDK-tagged

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Recombinant Human PRKAA1 Protein, MYC/DDK-tagged

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Cat.No. : PRKAA1-2953H
Product Overview : Recombinant Human PRKAA1 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.
Description : The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 63.8 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit [ Homo sapiens ]
Official Symbol : PRKAA1
Synonyms : AMPK; AMPKa1
Gene ID : 5562
mRNA Refseq : NM_006251
Protein Refseq : NP_006242
MIM : 602739
UniProt ID : Q13131

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