Recombinant Human PRKACB, GST-tagged, Active

• Cat.No.: PRKACB-395H
• Product Overview: Recombinant human full-length PKAcbeta was expressed by baculovirus inSf9 cellsusing an N-terminal GST tag. MW=65 kDa.

Specification

• Cat. No.: PRKACB-395H
• Description: The catalytic subunit C-beta of PKA (PKAcβ) is a member of the Ser/Thr protein kinase family (the PKA catalytic subunit consist of three gene products: C-alpha, C-beta, and C-gamma) and has been assigned to human chromosome region 1p36.1. PKAcβ is derived from a gene distinct from C-alpha and shows tissue-specific expression. At the amino acid level C-alpha and C-beta showed 93% homology.
• Source: Sf9 insect cells using baculovirus.
• Sequence: Full-length.
• Applications: Kinase Assay, Western Blot.
• Storage And Stability: Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Gene Information

• Gene Name: PRKACB protein kinase, cAMP-dependent, catalytic, beta [ Homo sapiens ]
• Synonyms: PRKACB; protein kinase, cAMP-dependent, catalytic, beta; PKACB; MGC9320; MGC41879; DKFZp781I2452; PKACb; cAMP-dependent protein kinase catalytic subunit beta; EC 2.7.11.11; PKA C-beta
• Gene ID: 5567
• mRNA Refseq: NM_002731
• Protein Refseq: NP_002722
• UniProt ID: P22694
• Chromosome Location: 1p36.1
• MIM: 176892
• Pathway: Apoptosis; Calcium signaling pathway; Chemokine signaling pathway; Dilated cardiomyopathy; Gap junction; GnRH signaling pathway; Hedgehog signaling pathway; Insulin signaling pathway; Melanogenesis; Long-term potentiation; Progesterone-mediated oocyte maturation; Wnt signaling pathway; Vibrio cholerae infection
• Function: ATP binding; nucleotide binding; transferase activity; cAMP-dependent protein kinase activity; cAMP-dependent protein kinase inhibitor activity; protein serine/threonine kinase activity; protein kinase binding